Marine ingredients in
Marine ingredients in sports nutrition partly by being metabolized to anti-inflammatory Specialized Pro- Resolving Mediators, SPMs, and eicosanoids. Additionally, nature´s most powerful antioxidant astaxanthin reduces muscle-inflammation and soreness, leading to faster restitution and shorter time to the next full-intensity performance. Many athletes struggle to maintain their body in shape off season. This is the time of the season when you build the foundation for seasonal performance and muscles, heart, joints, and ligaments are exposed to extraordinary strain. During resting periods, it can be a challenge to maintain the body composition. Well, we have good news! Zooca Lipids benefits body composition and both fat reduction and muscle growth have been demonstrated in clinical trials. So, why is that so? Free fatty acid receptors are broadly regarded as nutrient sensors and are involved in the regulation of both inflammatory and metabolic processes. One of these is the GPR120 (also known as FFA4) receptor which is expressed in several tissues in the body, especially within the distal intestine and colon, as well as in adipose tissue and macrophages. This is a receptor for medium- and long-chain unsaturated fatty acids, including omega-3 fatty acids. Recent studies have shown GPR120 to play cardinal roles in metabolic disorders via modulation of gut hormone secretion and insulin sensitivity and body weight regulation. Whereas other dietary lipids claim their effects due to rapid absorption, Zooca Lipids explains it the other way around. The liquid wax esters from Zooca Lipids are slowly digested, resulting in delayed release of multiple bioactive molecules. The unique chemistry of these new and natural lipids allows them to withstand the first line of digestive enzymes, letting the lipids reach the distal part of the digestive tract without compromising the bioavailability of the fatty acids. When the liquid wax ester molecules ultimately are cleaved during digestion, the release of highly potent fatty acids activates GPR120 receptors present in the tissue and exert its effects. Whereas EPA and DHA are among the more potent of the common FAs on GPR120, Stearidonic acid, SDA, has recently been shown to be one of the most potent agonists on this central receptor. SDA is the predominant omega-3 fatty acid in Zooca Lipids! This receptor activation helps the body finetune metabolism of sugar and fat, making it easier to maintain the optimal body composition. Athletes report that it is easier to maintain the ideal body weight and body composition during off-season. If you think this was a bit complicated, we will make it easy for you. Summarized, what you need to know is that this natural powerpack of natural fats and nutrients from the zooplankton Calanus finmarchicus benefits muscle performance and restitution, heart pumping efficiency and body composition. So, do like the little auk: take Zooca Lipids with you on your sporting adventures! For more information and insight into clinical and preclinical results, please reach out to Seanova contact@seanova.fr www.seanova.fr 22 No. 1 April/May 2022
Ceramides for skin health Photo © : AdobeStock/Liubov_Levytska Ceramides: science supported lipids for skin health Lea Marchal As more and more information regarding ageing skin and its causes becomes available, consumer awareness continues to increase at an unprecedented high. The rise of Holistic Beauty observed for a few years, is a clear indication that consumers are now viewing lifestyle as an important factor in the appearance of their skin, including dietary interventions. To make the most of this opportunity in the Beauty-from- Within category, brands must develop food supplements based on ingredients with demonstrated efficacy, from natural origin, good for the consumers and more respectful of the environment. Seppic, designer of natural branded active ingredients for the nutricosmetics field, sheds light on a solution related to these major trends: phytoceramides. Ceramides: their role in skin health and youth The skin is a three-layer organ constituted of the hypodermis, the dermis, and the epidermis. The latter layer of the epidermis is called the stratum corneum and acts as a barrier against the exterior environment. The stratum corneum is made of skin cells, called corneocytes, and of lipids found in the intercellular spaces. The lipids are of different nature (cholesterol, free fatty acids,...) and ceramides are the major lipid species as they are represented at 50 % in the stratum corneum’s matrix. They have an essential and structuring role in skin health by supporting the skin barrier function and maintaining the water permeability of the skin. When skin reserves of water are preserved, the skin remains well moisturized and plump, preventing the apparition of cracks and scales. However, when we age, the skin becomes particularly thin and fragile with an impaired skin barrier. The stratum corneum of the skin, and more particularly its lipids, go through significant changes under the course of ageing, resulting in pigmentation spots, loss of elasticity, wrinkles and exacerbated dryness. These changes are now linked with a significant decrease in ceramides 1 . No. 1 April/May 2022 23
